Minnesota State Highway 5 is a 76.347-mile-long (122.869 km) highway in Minnesota, which runs from its intersection with MN 19 and MN 22 in Gaylord and continues east and northeast to its eastern terminus at its intersection with MN 120 in Maplewood. The route passes through downtown Saint Paul.

Minnesota State Highway 22 (MN 22) is a 166.325-mile-long (267.674 km) highway in south-central and central Minnesota, which runs from Winnebago County Road R50 at the Iowa state line near Kiester and continues north to its northern terminus at its intersection with State Highway 23 in Richmond, west of St. Cloud.