The Miss South Carolina USA competition, previously known as Miss South Carolina Universe, is the pageant that selects the representative for the state South Carolina in the Miss USA pageant, and the name of the title held by that winner. The pageant has been produced by Paula Miles, the sister of Miss South Carolina USA 1979, Janice McDonald, since 1980, and it has been directed by RPM Productions.

Miss USA is an American beauty pageant that has been held annually since 1952 to select the entrant from United States in the Miss Universe pageant. The Miss Universe Organization operated both pageants, as well as Miss Teen USA, until 2020, when the organization announced it was licensing operation of the Miss USA and Miss Teen USA pageants to Crystle Stewart, Miss USA for 2008 prior to her suspension in October 2022, thus returning the said pageants to the Miss Universe Organization.