Mission San Gabriel Arcángel is a Californian mission and historic landmark in San Gabriel, California. It was founded by the Spanish Empire on "The Feast of the Birth of Mary," September 8, 1771, as the fourth of what would become twenty-one Spanish missions in California. San Gabriel Arcángel was named after the Archangel Gabriel and often referred to as the "Godmother of the Pueblo of Los Angeles."

The Spanish missions in California formed a series of 21 religious outposts or missions established between 1769 and 1833 in what is now the U.S. state of California. The missions were established by Catholic priests of the Franciscan order to evangelize indigenous peoples backed by the military force of the Spanish Empire. The missions were part of the expansion and settlement of New Spain through the formation of Alta California, expanding the empire into the most northern and western parts of Spanish North America. Civilian settlers and soldiers accompanied missionaries and formed settlements like the Pueblo de Los Ángeles.