Mission Santa Barbara is a Spanish mission in Santa Barbara, California, United States. Often referred to as the 'Queen of the Missions', it was founded by Padre Fermín Lasuén for the Franciscan order on December 4, 1786, the feast day of Saint Barbara, as the tenth mission of what would later become 21 missions in Alta California.

Santa Barbara is a coastal city in Santa Barbara County, California, of which it is also the county seat. Situated on a south-facing section of coastline, the longest such section on the West Coast of the United States excepting Alaska, the city lies between the steeply rising Santa Ynez Mountains and the Pacific Ocean. Santa Barbara's climate is often described as Mediterranean, and the city has been dubbed "The American Riviera". According to the 2020 U.S. Census, the city's population was 88,665.