The Mississippian Railway is a short line railroad operating from Amory, Mississippi, to Fulton, Mississippi. It is owned and operated by the Itawamba County Railroad Authority.

Amory is a city in Monroe County, Mississippi, United States. The population was 6,666 at the 2020 census, down from 7,316 in 2010. Located in the northeastern part of the state near the Alabama border, it was founded in 1887 as a railroad town by the Kansas City, Memphis and Birmingham Railroad. As a result, Cotton Gin Port, along the Tombigbee River to the east, was abandoned as businesses and people moved for railroad access.