Missoula Cemetery is the second oldest cemetery located in Missoula, Montana, with Fort Missoula Cemetery being the oldest. The Missoula Cemetery was first established in 1884 by the Missoula Valley Improvement Company, a corporation owned by prominent citizens Isadore Cohn, Frank Woody, William H.H. Dickinson and Thomas C Marshall. The land where the cemetery would be built was purchased from the Northern Pacific Railroad for $168. The cemetery was eventually sold to the City of Missoula in 1901, for the total of $1.

Capt. Christopher Powers Higgins was an American Army captain and later businessman who with Frank Worden founded the Hellgate Trading Post and the nearby city of Missoula, Montana. He erected one of the first lumber and flouring mills on the Clark Fork River near present Downtown Missoula as well as many of Missoula's first buildings and establishments. He was one of the original county commissioners, member of first legislature of the Montana Territory, and incorporator of The Montana Historical Society. Higgins Avenue and bridge as well as the Higgins block in Downtown Missoula are named after him. He is buried in Missoula Cemetery.