The Missouri River is a river in the Central and Mountain West regions of the United States. The nation's longest, it rises in the eastern Centennial Mountains of the Bitterroot Range of the Rocky Mountains of southwestern Montana, then flows east and south for 2,341 miles (3,767 km) before entering the Mississippi River north of St. Louis, Missouri. The river drains semi-arid watershed of more than 500,000 square miles (1,300,000 km2), which includes parts of ten U.S. states and two Canadian provinces. Although a tributary of the Mississippi, the Missouri River is slightly longer and carries a comparable volume of water. When combined with the lower Mississippi River, it forms the world's fourth-longest river system.

Missouri is a landlocked state in the Midwestern region of the United States. Ranking 21st in land area, it borders Iowa to the north, Illinois, Kentucky and Tennessee to the east, Arkansas to the south and Oklahoma, Kansas, and Nebraska to the west. In the south are the Ozarks, a forested highland, providing timber, minerals, and recreation. The Missouri River, after which the state is named, flows through the center and into the Mississippi River, which makes up the eastern border. With over six million residents, it is the 18th-most populous state of the country. The largest urban areas are St. Louis, Kansas City, Springfield, and Columbia; the capital is Jefferson City.