Mister X was a series of comic books first published in 1983–1990 by Canadian company Vortex Comics. Created by album and book cover designer Dean Motter, it was developed for a year in close collaboration with comic artist and illustrator Paul Rivoche, whose series of poster illustrations stirred up great interest in the project. The series published early work by comic artists who would later emerge as important alternative cartoonists, including Jaime Hernandez, Gilbert Hernandez, Mario Hernandez, Seth, Shane Oakley and D'Israeli.

Vortex Comics is a Canadian independent comic book publisher that began operation in 1982. Under the supervision of president, publisher, and editor Bill Marks, Vortex was known for such titles as Dean Motter's Mister X, Howard Chaykin's Black Kiss, and Chester Brown's Yummy Fur, the last of which was a pioneer of alternative comics. Vortex also earned a reputation for publishing Canadian comic book creators such as Brown, Ty Templeton, Ken Steacy, and Jeffrey Morgan.