Mizoram Presbyterian Church Synod is the largest Christian denomination in Mizoram, northeast India. It was a direct progeny of the Calvinistic Methodist Church in Wales. It was the first church in Mizoram and is now one of the constituent bodies of a larger denomination Presbyterian Church of India (PCI), which has its headquarters in Shillong, Meghalaya. The administrative body called the Mizoram Synod has its headquarters at Mission Veng, Aizawl. As the first church, it remains the largest denomination in Mizoram.

Mizoram is a landlocked state in northeast India, with Aizawl as its seat of government and largest city. Within India's northeast region, it is the southernmost state, sharing borders with three of the Seven Sister States, namely Tripura, Assam and Manipur, and also shares a 722-kilometre (449 mi) border with the neighbouring countries of Bangladesh and Myanmar. The state spans over an area of approximately 21,087 square kilometres, of which approximately 91% is forested. With an estimated population of 1.25 million in 2023, it is the second least populous state in the country.