Moctar Ouane is a Malian diplomat and politician who served as the acting Prime Minister of Mali from 27 September 2020 to 24 May 2021, between the 2020 Malian coup d'état and the 2021 Malian coup d'état. He also previously served in the government of Mali as Minister of Foreign Affairs from May 2004 to April 2011.

The 2021 Malian coup d'état began on the night of 24 May 2021 when the Malian Army led by Vice President Assimi Goïta captured President Bah N'daw, Prime Minister Moctar Ouane and Minister of Defence Souleymane Doucouré. Assimi Goïta, the head of the junta that led the 2020 Malian coup d'état, announced that N'daw and Ouane were stripped of their powers and that new elections would be held in 2022. It is the country's third coup d'état in ten years, following the 2012 and 2020 military takeovers, with the latter having happened only nine months earlier.