Mohammad-Reza Khatami is an Iranian reformist politician and nephrologist.

The Reformists are a political faction in Iran. Iran's "reform era" is sometimes said to have lasted from 1997 to 2005—the length of President Mohammad Khatami's two terms in office. The Council for Coordinating the Reforms Front is the main umbrella organization and coalition within the movement; however, there are reformist groups not aligned with the council, such as the Reformists Front.