Mokolo is the departmental capital and largest city of the Mayo-Tsanaga department, in the Far North Province of Cameroon. It is the fourth largest city in the Far North Province, after Maroua, Yagoua, and Kousséri. It is located in the Mandara Mountains that run along the Cameroonian-Nigerian border.

The Far North Region, also known as the Extreme North Region, is the northernmost and most populous constituent province of the Republic of Cameroon. It borders the North Region to the south, Chad to the east, and Nigeria to the west. The capital is Maroua.