Monroe is the largest city and county seat of Monroe County, Michigan, United States. The population was 20,462 as of the 2020 census. The city is bordered on the south by Monroe Charter Township, but the two are administered autonomously. Monroe is the core city in the Monroe metropolitan area, which is coterminous with Monroe County and had a population of 154,809 in 2020. Located on the western shores of Lake Erie approximately 20 miles (32 km) northeast of Toledo, Ohio, and 40 miles (64 km) southwest of Detroit, the city is part of the Detroit–Ann Arbor–Flint combined statistical area.

Monroe County is a county in the U.S. state of Michigan. As of the 2020 Census, the population was 154,809. The largest city and county seat is Monroe. The county was established as the second county in the Michigan Territory in 1817 and was named for then-President James Monroe. Monroe County is coterminous with the Monroe metropolitan statistical area.