Monson is a town in Piscataquis County, Maine, United States. The population was 609 at the 2020 census. The town is located on Route 15 which is a significant route north into the well known Moosehead Lake Region, to which Monson can be considered a gateway. This route eventually leads to the Canadian Province of Quebec.

Piscataquis County is a county located in the U.S. state of Maine. As of the 2020 census, its population was 16,800, making it Maine's least-populous county. Its county seat is Dover-Foxcroft. The county was incorporated on March 23, 1838, taken from the western part of Penobscot County and the eastern part of Somerset County. It is named for an Abenaki word meaning "branch of the river" or "at the river branch."