Montana State University Billings (or MSU Billings) is a public university in Billings, Montana. It is the state's third largest university. Its campus is located on 110 acres in downtown Billings. Formerly Eastern Montana Normal School at its founding in 1927, the Normal School changed its name to Eastern Montana College of Education in 1949. It was again renamed in 1965 as Eastern Montana College (EMC). It merged into the Montana University System in 1994 under its present name. Currently, the university offers over 100 specialized programs for certificates, associate, bachelor's, and master's degrees through the university's five colleges. The five colleges of Montana State University Billings are Liberal Arts & Social Sciences, Business, Health Professions and Science, Education, and City College.

Billings is the most populous city in the U.S. state of Montana, with a population of 117,116 as of the 2020 census. Located in the south-central portion of the state, it is the seat of Yellowstone County and the principal city of the Billings Metropolitan Area, which had a population of 184,167 in the 2020 census. With one of the largest trade areas in the United States, Billings is the trade and distribution center for much of Montana east of the Continental Divide. Billings is also the largest retail destination for much of the same area. The Billings Chamber of Commerce claims the area of commerce covers more than 125,000 square miles (320,000 km2). In 2009, it was estimated to serve over 500,000 people.