The Moon has appeared in fiction as a setting since at least classical antiquity. Throughout most of literary history, a significant portion of works depicting lunar voyages has been satirical in nature. From the late 1800s onwards, science fiction has successively focused largely on the themes of life on the Moon, first Moon landings, and lunar colonization.

Colonization of the Moon is a process or concept employed by some proposals for robotic or human exploitation and settlement endeavours on the Moon. Settling of the Moon is, therefore, a more specific concept of lunar habitation, for which the broader concept of colonization is often used as a synonym, a use that is contested in the light of colonialism.