Moss Point is a city in Jackson County, Mississippi, United States. The population was 12,147 in 2020, a decline from the figure of 13,704 in 2010. The Moss Point Historic District and several individual buildings are listed on the National Register of Historic Places' Jackson County listings.

Jackson County is a county located in the U.S. state of Mississippi. As of the 2020 census, the population was 143,252, making it the fifth-most populous county in Mississippi. Its county seat is Pascagoula. The county was named for Andrew Jackson, general in the United States Army and afterward President of the United States.