Mossley Hill railway station is in the suburbs of Liverpool in the north west of England. The station is operated by Northern Trains.

The St Helens and Runcorn Gap Railway was an early railway line owned by a company of the same name in Lancashire, England, which opened in 1833. It was later known as St Helens Railway. It ran originally from the town of St Helens to the area which would later develop into the town of Widnes. Branches were opened to Garston, Warrington and Rainford. The company was taken over by the London and North Western Railway in 1864. The line from St Helens to Widnes and the branch to Rainford are now closed, the latter terminating at the Pilkington Glass' Cowley Hill works siding near Gerard's Bridge, but part of the lines to Garston and to Warrington are still in operation.