Mount Bona is one of the major mountains of the Saint Elias Mountains in eastern Alaska, and is the fifth-highest independent peak in the United States. It is either the tenth- or eleventh-highest peak in North America. Mount Bona and its adjacent neighbor Mount Churchill are both large ice-covered stratovolcanoes. Bona has the distinction of being the highest volcano in the United States and the fourth-highest in North America, outranked only by the three highest Mexican volcanoes, Pico de Orizaba, Popocatépetl, and Iztaccíhuatl. Its summit is a small stratovolcano on top of a high platform of sedimentary rocks.

The Saint Elias Mountains are a subgroup of the Pacific Coast Ranges, located in southeastern Alaska in the United States, Southwestern Yukon and the very far northwestern part of British Columbia in Canada. The range spans Wrangell-St. Elias National Park and Preserve in the United States and Kluane National Park and Reserve in Canada and includes all of Glacier Bay National Park in Alaska. In Alaska, the range includes parts of the city/borough of Yakutat and the Hoonah-Angoon and Valdez-Cordova census areas.