Mount Holyoke College is a private liberal arts women's college in South Hadley, Massachusetts, United States. It is the oldest member of the historic Seven Sisters colleges, a group of historically female colleges in the Northeastern United States. The college was founded in 1837 as the Mount Holyoke Female Seminary by Mary Lyon, a pioneer in education for women. Mount Holyoke is part of the Five College Consortium in Western Massachusetts.

A female seminary is a private educational institution for women, popular especially in the United States in the nineteenth and early twentieth centuries, when opportunities in educational institutions for women were scarce. The movement was a significant part of a remarkable transformation in American education in the period 1820–1850. Supporting academic education for women, the seminaries were part of a large and growing trend toward women's 'equality'. Some trace its roots to 1815, and characterize it as at the confluence of various liberation movements. Some of the seminaries gradually developed as four-year colleges.