Mount Sterling is a village in Madison County, Ohio, United States. The population was 1,945 at the 2020 census. It is a part of the Columbus, Ohio Metropolitan Statistical Area.

Madison County is a county located in the central portion of the U.S. state of Ohio. As of the 2020 census, the population was 43,824. Its county seat is London. The county is named for James Madison, President of the United States and was established on March 1, 1810.