The Mousterian is an archaeological industry of stone tools, associated primarily with the Neanderthals in Europe, and to the earliest anatomically modern humans in North Africa and West Asia. The Mousterian largely defines the latter part of the Middle Paleolithic, the middle of the West Eurasian Old Stone Age. It lasted roughly from 160,000 to 40,000 BP. If its predecessor, known as Levallois or Levallois-Mousterian, is included, the range is extended to as early as c. 300,000–200,000 BP. The main following period is the Aurignacian of Homo sapiens.

The Aurignacian is an archaeological industry of the Upper Paleolithic associated with Early European modern humans (EEMH) lasting from 43,000 to 26,000 years ago. The Upper Paleolithic developed in Europe some time after the Levant, where the Emiran period and the Ahmarian period form the first periods of the Upper Paleolithic, corresponding to the first stages of the expansion of Homo sapiens out of Africa. They then migrated to Europe and created the first European culture of modern humans, the Aurignacian.