The Muhyiddin cabinet was formed on 10 March 2020, nine days after Muhyiddin Yassin was appointed as the 8th Prime Minister of Malaysia and dissolved 17 months and 6 days later on 16 August 2021, the day when Muhyiddin submitted his resignations as PM and of this cabinet. It was the 21st cabinet of Malaysia formed since independence. This cabinet was also known as the Perikatan Nasional Cabinet (PN-Cabinet) which combined 15 political parties from the Perikatan Nasional (PN) component parties, with Barisan Nasional (BN) component parties, Gabungan Parti Sarawak (GPS) component parties and United Sabah Party (PBS) as allied partners providing confidence and supply.

The prime minister of Malaysia is the head of government of Malaysia. The prime minister directs the executive branch of the federal government. The Yang di-Pertuan Agong appoints the prime minister as a member of Parliament (MP) who, in his opinion, is most likely to command the confidence of a majority of MPs. The Prime Minister is usually the leader of the party winning the most seats in a general election.