Muller's ratchet
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In evolutionary genetics, Muller's ratchet is a process which, in the absence of recombination, results in an accumulation of irreversible deleterious mutations. That happens because in the absence of
Illustration of chromosome crossover during genetic recombination
Hermann Joseph Muller
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Hermann Joseph Muller was an American geneticist who was awarded the 1946 Nobel Prize in Physiology or Medicine "for the discovery of the production of mutations by means of X-ray irradiation". Muller
Muller's ratchet
…In evolutionary genetics, Muller's ratchet (named after American geneticist Hermann Joseph Muller, by analogy with a ratchet effect) is a process which, in the absence of recombination (especially in an asexual population), results in an accumulation…
Muller in 1952
Muller's house in Bloomington, Indiana