A multiple independently targetable reentry vehicle (MIRV) is an exoatmospheric ballistic missile payload containing several warheads, each capable of being aimed to hit a different target. The concept is almost invariably associated with intercontinental ballistic missiles carrying thermonuclear warheads, even if not strictly being limited to them. An intermediate case is the multiple reentry vehicle (MRV) missile which carries several warheads which are dispersed but not individually aimed. All nuclear-weapon states except Pakistan and North Korea are currently confirmed to have deployed MIRV missile systems. Israel is suspected to possess or be in the process of developing MIRVs.

A ballistic missile (BM) is a type of missile that uses projectile motion to deliver warheads on a target. These weapons are powered only during relatively brief periods—most of the flight is unpowered. Short-range ballistic missiles (SRBM) typically stay within the Earth's atmosphere, while most larger missiles are exo-atmospheric. The largest ICBMs are capable of full orbital flight. These weapons are in a distinct category from cruise missiles, which are aerodynamically guided in powered flight and thus restricted to the atmosphere.