Multiple sequence alignment
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Multiple sequence alignment is the process or the result of sequence alignment of three or more biological sequences, generally protein, DNA, or RNA. These alignments are used to infer evolutionary re
Non-homologous exon alignment by an iterative method (a), and by a phylogeny-aware method (b)
Clustal
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Clustal is a computer program used for multiple sequence alignment in bioinformatics. It is one of the most widely cited bioinformatics software with two of its academic publications amongst the top 1
Multiple sequence alignment
…methods are efficient enough to implement on a large scale for many (100s to 1000s) sequences. A popular progressive alignment method has been the Clustal family. ClustalW is used extensively for phylogenetic tree construction, in spite of the author's explicit warnings that unedited alignments should not…
Multiple sequence alignment of CDK4 protein generated with ClustalW. Arrows indicate point mutations.