Mumbai City Football Club is an Indian professional football club based in Mumbai, Maharashtra. It is part of the City Football Group. The club competes in the Indian Super League, the top tier of the Indian football league system. Mumbai City is one of the most successful clubs in the history of the ISL. They are the first club to win both the League Winners Shield and the ISL title in a single season, which it accomplished in the 2020–21 season. They are the only team to win the ISL league winners shield twice.

The 2021–22 Indian Super League season was the eighth season of the Indian Super League (ISL) since its formation in 2013 and the 26th season of the top division of Indian football league system. The season started on 19 November 2021 and concluded with the final on 20 March 2022. Except for the final, it was hosted behind closed doors across three venues in Goa due to the COVID-19 pandemic in India.