Murad III was the sultan of the Ottoman Empire from 1574 until his death in 1595. His rule saw battles with the Habsburgs and exhausting wars with the Safavids. The long-independent Morocco was for a time made a vassal of the empire but regained independence in 1582. His reign also saw the empire's expanding influence on the eastern coast of Africa. However, the empire was beset by increasing corruption and inflation from the New World which led to unrest among the Janissary and commoners. Relations with Elizabethan England were cemented during his reign as both had a common enemy in the Spanish. He was also a great patron of the arts, commissioning the Siyer-i-Nebi and other illustrated manuscripts.

Selim II, also known as Selim the Blond or Selim the Drunkard, was the sultan of the Ottoman Empire from 1566 until his death in 1574. He was a son of Suleiman the Magnificent and his wife Hurrem Sultan. Selim had been an unlikely candidate for the throne until his brother Mehmed died of smallpox, his half-brother Mustafa was strangled to death by the order of his father and his brother Bayezid was killed on the order of his father after a rebellion against him and Selim.