Murder by Numbers is a 2002 American psychological thriller film produced and directed by Barbet Schroeder and starring Sandra Bullock in the main role alongside Ben Chaplin, Ryan Gosling, and Michael Pitt. It is loosely based on the Leopold and Loeb case. The film was screened at the 2002 Cannes Film Festival, but was not entered in competition.

Barbet Schroeder is an Iranian-born Swiss film director and producer who started his career in French cinema in the 1960s, working with directors of the French New Wave such as Jean-Luc Godard, Jacques Rivette and Eric Rohmer.