Murder on the Orient Express is a 2017 mystery film co-produced and directed by Kenneth Branagh from a screenplay by Michael Green, based on the 1934 novel of the same name by Agatha Christie. The film stars an ensemble cast with Branagh as Hercule Poirot, alongside Tom Bateman, Penélope Cruz, Willem Dafoe, Judi Dench, Johnny Depp, Josh Gad, Derek Jacobi, Leslie Odom Jr., Michelle Pfeiffer, and Daisy Ridley. The plot follows Poirot, a world-renowned detective, as he investigates a murder on the luxury Orient Express train service in the 1930s.

A mystery film is a film that revolves around the solution of a problem or a crime. It focuses on the efforts of the detective, private investigator or amateur sleuth to solve the mysterious circumstances of an issue by means of clues, investigation, and clever deduction. Mystery films include, but are not limited to, films in the genre of detective fiction.