Murrells Inlet is an unincorporated area and census-designated place in Georgetown County, South Carolina, United States. The population was 7,547 at the 2010 census. It is about 13 miles south of Myrtle Beach, South Carolina and 21 miles north of Georgetown, the county seat.

Georgetown County is a county located in the U.S. state of South Carolina. As of the 2020 census, the population was 63,404. Its county seat is Georgetown. The county was founded in 1769. It is named for George III of the United Kingdom.