Murzuq is one of the districts of Libya. It is in the south of the country. Its capital is Murzuk. The city was occupied by the Ottoman Empire in 1578 and served as the capital of Fezzan off and on until the Ottomans ceded Libya to Italy in 1912. It was not occupied by the Italians until 1914.

Murzuk, Murzuq, Murzug or Merzug is an oasis town and the capital of the Murzuq District in the Fezzan region of southwest Libya. It lies on the northern edge of the Murzuq Desert, an extremely arid region of ergs or great sand dunes which is part of the greater Sahara Desert.