Musca is a small constellation in the deep southern sky. It was one of 12 constellations created by Petrus Plancius from the observations of Pieter Dirkszoon Keyser and Frederick de Houtman, and it first appeared on a celestial globe 35 cm (14 in) in diameter published in 1597 in Amsterdam by Plancius and Jodocus Hondius. The first depiction of this constellation in a celestial atlas was in Johann Bayer's Uranometria of 1603. It was also known as Apis for 200 years. Musca remains below the horizon for most Northern Hemisphere observers.

Petrus Plancius was a Dutch-Flemish astronomer, cartographer and clergyman. He was born as Pieter Platevoet in Dranouter, now in Heuvelland, West Flanders. He studied theology in Germany and England. At the age of 24 he became a minister in the Dutch Reformed Church.