The Museum Wiesbaden is a two-branch museum of art and natural history in the Hessian capital of Wiesbaden, Germany. It is one of the three Hessian State museums, in addition to the museums in Kassel and Darmstadt.

Wiesbaden is the capital of the German state of Hesse, and the second-largest Hessian city after Frankfurt am Main. With around 283,000 inhabitants, it is Germany's 24th-largest city. Wiesbaden forms a conurbation with a population of around 500,000 with the neighbouring city of Mainz. This conurbation is in turn embedded in the Rhine-Main Metropolitan Region—Germany's second-largest metropolitan region after Rhine-Ruhr—which also includes the nearby cities of Frankfurt am Main, Darmstadt, Offenbach am Main, and Hanau, and has a combined population exceeding 5.8 million.