The Muslim conquest of Transoxiana or Arab conquest of Transoxiana were the 7th and 8th century conquests, by Umayyad and Abbasid Arabs, of Transoxiana, the land between the Oxus and Jaxartes rivers, a part of Central Asia that today includes all or parts of Uzbekistan, Tajikistan, Kazakhstan, and Kyrgyzstan.

Transoxiana or Transoxania is the Latin name for the region and civilization located in lower Central Asia roughly corresponding to modern-day eastern Uzbekistan, western Tajikistan, parts of southern Kazakhstan, parts of Turkmenistan and southern Kyrgyzstan. The name was first coined by Alexander the Great in the 4th century BC when Alexander's troops were able to conquer the region. The region may have had a similar Greek name in the days of Alexander the Great, but the earlier Greek name is no longer known. Geographically, it is the region between the rivers Amu Darya to its south and the Syr Darya to its north.