My Favorite Murder is a weekly true crime comedy podcast hosted by American comedians Karen Kilgariff and Georgia Hardstark. The first episode was released in January 2016. The podcast debuted at #25 on the iTunes podcast charts and peaked at #3 on April 27, 2018. Weekly episodes regularly land within the iTunes' Top 10 Comedy Podcast chart. As of 2020, the podcast gets 35 million downloads per month.

Karen Kilgariff is an American writer, comedian, singer, author, actress, television producer, and podcast host. She began her career as a stand up comedian in the early 1990s and later became a television actress, most notably as a cast member on Mr. Show. She has written for many comedy television shows, including being the head writer on The Rosie Show, The Ellen Degeneres Show and The Pete Holmes Show.