My Sweet Audrina is a 1982 novel by V. C. Andrews. It was the only stand-alone novel published during Andrews' lifetime and was a number-one best-selling novel in North America. The story takes place in the Mid-Atlantic United States during the 1960s and 1970s. The story features diverse subjects, such as brittle bone disease, rape, posttraumatic stress disorder and diabetes, in the haunting setting of a Victorian-era mansion near the fictitious River Lyle.

Cleo Virginia Andrews, better known as V. C. Andrews or Virginia C. Andrews, was an American novelist. She was best known for her 1979 novel Flowers in the Attic, which inspired two movie adaptations and four sequels. While her novels are not classified by her publisher as Young Adult, their young protagonists have made them popular among teenagers for decades. After her death in 1986, a ghostwriter who was initially hired to complete two unfinished works has continued to publish books under her name.