Myrmekiaphila is a genus of North American mygalomorph trapdoor spiders in the family Euctenizidae, and was first described by G. F. Atkinson in 1886. All described species are endemic to the southeastern United States.

Ctenizidae is a small family of mygalomorph spiders that construct burrows with a cork-like trapdoor made of soil, vegetation, and silk. They may be called trapdoor spiders, as are other, similar species, such as those of the families Liphistiidae, Barychelidae, and Cyrtaucheniidae, and some species in the Idiopidae and Nemesiidae. The name comes from the distinctive behavior of the spiders to construct trapdoors, and ambush prey from beneath them.