Myspace is an American social networking website. From 2005 to 2008, it was the largest social networking site in the world, it was headquartered in California. Myspace was acquired by News Corporation in July 2005 for $580 million, in June 2006 surpassed Google as the most visited website in the United States. In April 2008, Myspace was overtaken by Facebook in the number of unique worldwide visitors and was surpassed in the number of unique U. S. visitors in May 2009, though Myspace generated $800 million in revenue during the 2008 fiscal year. Since the number of Myspace users has declined in spite of several redesigns; as of January 2018, Myspace was ranked 4,153 by total Web traffic, 1,657 in the United States. Myspace had a significant influence on pop culture and music and created a computer game platform that launched the successes of Zynga and RockYou, among others. Despite an overall decline, in 2015 Myspace still had 50.6 million unique monthly visitors and had a pool of over 1 billion active and inactive registered users.

In June 2009, Myspace employed 1,600 employees. In June 2011, Specific Media Group and Justin Timberlake jointly purchased the company for $35 million. On February 11, 2016, it was announced that Myspace and its parent company had been purchased by Time Inc. Time Inc. was in turn purchased by the Meredith Corporation on January 31, 2018. In August 2003, several eUniverse employees with Friendster accounts saw potential in its social networking features; the group decided to mimic the more popular features of the website. Within 10 days, the first version of Myspace was ready for launch, implemented using ColdFusion. A complete infrastructure of finance, human resources, technical expertise and server capacity was available for the site; the project was overseen by Brad Greenspan, who managed Chris DeWolfe, Josh Berman, Tom Anderson, a team of programmers and resources provided by eUniverse. The first Myspace users were eUniverse employees; the company held contests to see. EUniverse used its 20 million users and e-mail subscribers to breathe life into Myspace, move it to the head of the pack of social networking websites.

A key architect was tech expert Toan Nguyen who helped stabilize the Myspace platform when Brad Greenspan asked him to join the team. Co-founder and CTO Aber Whitcomb played an integral role in software architecture, utilizing the superior development speed of ColdFusion over other dynamic database driven server-side languages of the time. Despite over ten times the number of developers, developed in JavaServer Pages, could not keep up with the speed of development of Myspace and cfm. For example, users could customize the background and feel of pages on MySpace; the domain was owned by, Inc. intended until 2002 for use as an online data storage and sharing site. By late 2003, it was transitioned from a file storage service to a social networking site. A friend, who worked in the data storage business, reminded Chris DeWolfe that he had earlier bought the domain DeWolfe suggested. Brad Greenspan nixed the idea, believing that keeping Myspace free was necessary to make it a successful community.

Myspace gained popularity among teenagers and young adults. In February 2005, DeWolfe held talks with Mark Zuckerberg over acquiring Facebook but DeWolfe rejected Zuckerberg's $75 million offer; some employees of Myspace, including DeWolfe and Berman, were able to purchase equity in the property before MySpace and its parent company eUniverse was bought. In July 2005, in one of the company's first major Internet purchases, Rupert Murdoch's News Corporation purchased Myspace for US$580 million. News Corporation had beat out Viacom by offering a higher price for the website, the purchase was seen as a good investment at the time. Of the $580 million purchase price $327 million has been attributed to the value of Myspace according to the financial adviser fairness opinion. Within a year, Myspace had tripled in value from its purchase price. News Corporation saw the purchase as a way to capitalize on Internet advertising and drive traffic to other News Corporation properties. After losing the bidding war for Myspace, Viacom chairman Sumner Redstone stunned the entertainment industry in September 2006 when he fired Tom Freston from the position of CEO. Redstone believed that the failure to acquire MySpace contributed to the 20% drop in Viacom's stock price in 2006 up to the date of Freston's ouster.

Freston's successor as CEO, Philippe Dauman, was quoted as saying "never let another competitor beat us to the trophy." Redstone told interviewer Charlie Rose that losing MySpace had been "humiliating," adding, "MySpace was sitting there for the taking for $500 million" In January 2006, Fox announced plans to launch a UK version of Myspace in a bid to "tap into the UK music scene," which they did. They launched similar versions in other countries; the 100 millionth account was created on August 2006, in the Netherlands. On November 1, 2007, Myspace and Bebo joined the Google-led OpenSocial alliance, which included Friendster, Hi5, LinkedIn, Plaxo and Six Apart. OpenSocial was to promote a common set of standards for software developers to write programs for social networks. Facebook remained independent. Google had been unsuccessful in building its own social net

Cannabinoid Research Initiative of Saskatchewan

The Cannabinoid Research Initiative of Saskatchewan was founded in 2017 as an interdisciplinary research team of clinician researchers, basic scientists, social scientists. CRIS aims to obtain scientific evidence about the application of Cannabinoids and Medical cannabis to humans and animals, for health and disorders; the team was based at the University of Saskatchewan, in Saskatoon, Canada but includes researchers based at the University of Regina and University of Alberta. A strategic management executive committee coordinates activities and develops research opportunities; the sections of CRIS include: Analytical Evaluations, Human Clinical Studies, Biomedical studies, Veterinary Sciences, Knowledge Translation and Studies of Cannabinoids and Society. CRIS members participate in the Canadian Consortium for the Investigation of Cannabinoids, the International Cannabinoid Research Society; the CARE-E clinical trial of a cannabis oil with high cannabidiol content with pediatric patients with refractory epilepsy was a key factor in initiating the research initiative.

The CARE-E trial is a multi-center phase one trial that has open enrollment in five Canadian cities. The CARE-E trial received extensive media coverage; the therapeutic effect of pure cannabidiol on Dravet Syndrome was reported in the New England Journal of Medicine The CRIS group has expanded to biomedical science studies of the pharmacology of cannabinoids and synthetic cannabinoids. Drug Discovery Research Group - Determinants of neonatal exposure risk when breastfeeding mothers require medications. Research into the health benefits of flaxseed lignans and their underlying mechanism of action. Multiple Sclerosis Research - Epidemiology and pharmacoepidemiology of MS. Clinical trials Clinical trials looking at cannabis in pediatric neurological disease. Neuro-degenerative and neuro-metabolic disorders of childhoodType 1 cannabinoid receptor Pharmacology of the endocannabinoid system and the type 1 cannabinoid receptor. Microbiome studies Project under development by the Links Lab Knowledge Translation Medication adherence, patient education and interprofessional education.

Chronic Disease studies Use of interdisciplinary teams in chronic disease management, focusing on delivering diabetes care to immigrant and Aboriginal populations.'Cannabinoid Research Initiative of Saskatchewan"Canadian Consortium for the Investigation of Cannabinoids"International Cannabinoid Research Society' Cannabis portal Cannabidiol Charlotte's web Cannabis Cannabis Legal history of cannabis in Canada

North Adams, Michigan

North Adams is a village in Adams Township of Hillsdale County in the U. S. state of Michigan. The population was 477 at the 2010 census; the town is notable for being referenced in the Home Improvement episode "You're Driving Me Crazy, You're Driving Me Nuts." According to the United States Census Bureau, the village has a total area of 0.52 square miles, all land. As of the census of 2010, there were 477 people, 189 households, 137 families living in the village; the population density was 917.3 inhabitants per square mile. There were 219 housing units at an average density of 421.2 per square mile. The racial makeup of the village was 98.1% White, 0.4% Native American, 0.4% Asian, 0.2% from other races, 0.8% from two or more races. Hispanic or Latino of any race were 0.2% of the population. There were 189 households of which 32.3% had children under the age of 18 living with them, 55.6% were married couples living together, 13.8% had a female householder with no husband present, 3.2% had a male householder with no wife present, 27.5% were non-families.

23.8% of all households were made up of individuals and 10% had someone living alone, 65 years of age or older. The average household size was 2.52 and the average family size was 3.00. The median age in the village was 40.2 years. 24.5% of residents were under the age of 18. The gender makeup of the village was 52.0 % female. As of the census of 2000, there were 514 people, 204 households, 144 families living in the village; the population density was 974.5 per square mile. There were 215 housing units at an average density of 407.6 per square mile. The racial makeup of the village was 0.58 % Native American, 0.19 % from other races. Hispanic or Latino of any race were 1.95% of the population. There were 204 households out of which 31.9% had children under the age of 18 living with them, 56.9% were married couples living together, 6.9% had a female householder with no husband present, 29.4% were non-families. 26.0% of all households were made up of individuals and 9.8% had someone living alone, 65 years of age or older.

The average household size was 2.52 and the average family size was 3.01. In the village, the population was spread out with 26.5% under the age of 18, 8.6% from 18 to 24, 28.0% from 25 to 44, 23.5% from 45 to 64, 13.4% who were 65 years of age or older. The median age was 35 years. For every 100 females, there were 108.1 males. For every 100 females age 18 and over, there were 108.8 males. The median income for a household in the village was $38,523, the median income for a family was $42,813. Males had a median income of $30,774 versus $22,750 for females; the per capita income for the village was $19,850. About 1.3% of families and 3.2% of the population were below the poverty line, including 1.6% of those under age 18 and 7.7% of those age 65 or over