The N22 road is a national primary road in Ireland which goes through counties Kerry and Cork, from Tralee in the west through Killarney, Macroom and Ballincollig to Cork City Centre in the east.

A national primary road is a road classification in Ireland. National primary roads form the major routes between the major urban centres. There are 2649 km of national primary roads. This category of road has the prefix "N" followed by one or two digits. Motorways are prefixed "M" followed by one or two digits.