The National Aeronautics and Space Administration is an independent agency of the U.S. federal government responsible for the civil space program, aeronautics research, and space research. Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the U.S. space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo Moon landing missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station along with the Commercial Crew Program, and oversees the development of the Orion spacecraft and the Space Launch System for the lunar Artemis program.

Project Gemini was the second United States human spaceflight program to fly. Conducted after the first American manned space program, Project Mercury, while the Apollo program was still in early development, Gemini was conceived in 1961 and concluded in 1966. The Gemini spacecraft carried a two-astronaut crew. Ten Gemini crews and 16 individual astronauts flew low Earth orbit (LEO) missions during 1965 and 1966.