NGC 4414 is an unbarred spiral galaxy about 62 million light-years away in the constellation Coma Berenices. It is a flocculent spiral galaxy, with short segments of spiral structure but without the dramatic well-defined spiral arms of a grand design spiral. Four supernovae have been observed in this galaxy: SN 1974G, SN 2013df, SN 2021J, and SN 2023hlf.

Coma Berenices is an ancient asterism in the northern sky, which has been defined as one of the 88 modern constellations. It is in the direction of the fourth galactic quadrant, between Leo and Boötes, and it is visible in both hemispheres. Its name means "Berenice's Hair" in Latin and refers to Queen Berenice II of Egypt, who sacrificed her long hair as a votive offering. It was introduced to Western astronomy during the third century BC by Conon of Samos and was further corroborated as a constellation by Gerardus Mercator and Tycho Brahe. It is the only modern constellation named for a historic person.