Nagarjunsagar-Srisailam Tiger Reserve is the largest tiger reserve in India. The reserve spreads over five districts, Nandyal District, Prakasam District, Palnadu District, Nalgonda District and Mahabub Nagar district. The total area of the tiger reserve is 3,728 km2 (1,439 sq mi). The core area of this reserve is 1,200 km2 (460 sq mi). The reservoirs and temples of Srisailam are major attraction for many tourists and pilgrims. It is the largest tiger reserve forest in India and is located inside Nallamala forest area.

The Bengal tiger is a population of the Panthera tigris tigris subspecies and the nominate tiger subspecies. It ranks among the biggest wild cats alive today. It is considered to belong to the world's charismatic megafauna.