Nain is the northernmost permanent settlement in the Canadian province of Newfoundland and Labrador, within the Nunatsiavut region, located about 370 km (230 mi) by air from Happy Valley-Goose Bay. The town was established as a Moravian mission in 1771 by Jens Haven and other missionaries. As of 2021, the population is 1,204 mostly Inuit and mixed Inuit-European. Nain is the administrative capital of the autonomous region of Nunatsiavut.

Nunatsiavut is an autonomous area claimed by the Inuit in Newfoundland and Labrador, Canada. The settlement area includes territory in Labrador extending to the Quebec border. In 2002, the Labrador Inuit Association submitted a proposal for limited autonomy to the government of Newfoundland and Labrador. The constitution was ratified on December 1, 2005, at which time the Labrador Inuit Association ceased to exist, and the new Government of Nunatsiavut was established, initially being responsible for health, education and cultural affairs. It is also responsible for setting and conducting elections, the first of which was executed in October 2006. An election for the ordinary members of the Nunatsiavut Assembly was held on May 4, 2010. Its incumbent president is Johannes Lampe who assumed office in 2016.