The Naples–Salerno high-speed railway line is a link in the Italian high-speed rail network opened in June 2008. The 29-kilometre-long (18 mi) line is one of the new high-speed lines being built to strengthen rail transport system in Italy and in particular freight and passenger transport in Campania. The line is part of Corridor 1 of the European Union's Trans-European high-speed rail network, which connects Berlin and Palermo.

High-speed rail in Italy consists of two lines connecting most of the country's major cities. The first line connects Turin to Salerno via Milan, Bologna, Florence, Rome and Naples, the second runs from Turin to Venice via Milan and Verona, and is under construction in parts. Trains are operated with a top speed of 300 km/h (190 mph).