Nathaniel Macon was an American politician who represented North Carolina in both houses of Congress. He was the fifth speaker of the House, serving from 1801 to 1807. He was a member of the United States House of Representatives from 1791 to 1815 and a member of the United States Senate from 1815 to 1828. He opposed ratification of the United States Constitution and the Federalist economic policies of Alexander Hamilton. From 1826 to 1827, he served as President pro tempore of the United States Senate. Thomas Jefferson dubbed him "Ultimus Romanorum"—"the last of the Romans".

The speaker of the United States House of Representatives, commonly known as the speaker of the House, is the presiding officer of the United States House of Representatives. The office was established in 1789 by Article I, Section II, of the U.S. Constitution. By custom and House rules, the speaker is the political and parliamentary leader of the House and is simultaneously its presiding officer, de facto leader of the body's majority party, and the institution's administrative head. Speakers also perform various other administrative and procedural functions. Given these several roles and responsibilities, the speaker usually does not personally preside over debates—that duty is instead delegated to members of the House from the majority party—nor regularly participate in floor debates.