Natick is a town in Middlesex County, Massachusetts, United States. It is near the center of the MetroWest region of Massachusetts, with a population of 37,006 at the 2020 census. 10 miles (16 km) west of Boston, Natick is part of the Greater Boston area. Massachusetts's center of population was in Natick at the censuses of 2000–2020, most recently in the vicinity of Hunters Lane.

Daniel Takawambait was likely the first ordained Native American Christian pastor in North America, and served the church in the praying town of Natick, Massachusetts from 1683 to 1716. Takawambait also advocated for indigenous land rights in colonial Massachusetts, and authored at least one publication.