The French National Museum of Natural History, known in French as the Muséum national d'histoire naturelle, is the national natural history museum of France and a grand établissement of higher education part of Sorbonne Universities. The main museum, with four galleries, is located in Paris, France, within the Jardin des Plantes on the left bank of the River Seine. It was formally founded in 1793, during the French Revolution, but was begun even earlier in 1635 as the royal garden of medicinal plants. The museum now has 14 sites throughout France.

René Louiche Desfontaines was a French botanist.