The National Renewable Energy Laboratory (NREL) in the US specializes in the research and development of renewable energy, energy efficiency, energy systems integration, and sustainable transportation. NREL is a federally funded research and development center sponsored by the Department of Energy and operated by the Alliance for Sustainable Energy, a joint venture between MRIGlobal and Battelle. Located in Golden, Colorado, NREL is home to the National Center for Photovoltaics, the National Bioenergy Center, and the National Wind Technology Center.

The United States Department of Energy National Laboratories and Technology Centers is a system of laboratories overseen by the United States Department of Energy (DOE) for scientific and technological research. The primary mission of the DOE national laboratories is to conduct research and development (R&D) addressing national priorities: energy and climate, the environment, national security, and health. Sixteen of the seventeen DOE national laboratories are federally funded research and development centers administered, managed, operated and staffed by private-sector organizations under management and operating (M&O) contracts with the DOE. The National Laboratory system was established in the wake of World War II, during which the United States had quickly set-up and pursued advanced scientific research in the sprawling Manhattan Project.