The National Theatre was opened in 1992 to spearhead the Theatre movement in Ghana by providing a multi-functional venue for concerts, dance, drama and musical performances, screenplays, exhibitions and special events. In Ghana, theatre as an artistic form has existed for centuries in the traditional dramatic expressions of society, however, the National Theatre Movement (NTM) was conceived around the time of Ghana's independence in 1957 to help remold the new nation's cultural identity. The theatre is governed by the National Theatre Law 1991, PNDC Law 259. The building houses the three resident companies of the National Dance Company, the National Symphony Orchestra, and the National Theatre Players.

Accra is the capital and largest city of Ghana, located on the southern coast at the Gulf of Guinea, which is part of the Atlantic Ocean. As of 2021 census, the Accra Metropolitan District, 20.4 km2 (7.9 sq mi), had a population of 284,124 inhabitants, and the larger Greater Accra Region, 3,245 km2 (1,253 sq mi), had a population of 5,455,692 inhabitants. In common usage, the name "Accra" often refers to the territory of the Accra Metropolitan District as it existed before 2008, when it covered 199.4 km2 (77.0 sq mi). This territory has since been split into 13 local government districts: 12 independent municipal districts and the reduced Accra Metropolitan District (20.4 km2), which is the only district within the capital to be granted city status. This territory of 199.4 km2 contained 1,782,150 inhabitants at the 2021 census, and serves as the capital of Ghana, while the district under the jurisdiction of the Accra Metropolitan Assembly proper (20.4 km2) is distinguished from the rest of the capital as the "City of Accra".